Research Ideas

These research questions have been submitted by iConquerMS participants as part of the Our Questions Have Power program. iConquerMS participants can vote or comment on the questions they most want to see answered by research.

To vote on a question, first make sure you LOGIN to your iConquerMS account or JOIN iConquerMS then LOGIN. Then click the “Vote or Comment” button on the question and answer these questions: .

  • Do you agree that answering this question should be a high priority?.
  • Would the results of research on this question be helpful to you? .
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    Other Researchers

    Could the COVID-19 vaccine trigger the onset of MS in those who are already at a higher risk of developing it, such as direct relatives of people diagnosed with MS?

    This would mean tracking or gathering info on direct-line relatives and whether they show symptoms or get diagnosed with MS at a later date.
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    iConquerMS

    Does the COVID-19 vaccine have the potential to help resolve residual neurological symptoms in people with MS, based on evidence of improvement in fatigue and cognitive issues seen in COVID long haulers?

    I would like to know if individuals with MS are being tracked for symptom improvement as well after being vaccinated. https://www.medscape.com/viewarticle/947592#vp_1
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    Other Researchers

    How should patients proceed if they are having a relapse when their 2nd vaccine dose is due?

    I'd like further information about this especially for a relapse that presently does not require steroids.
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    iConquerMS

    What strategies work best to prevent side effects of COVID-19 vaccines from worsening MS symptoms?

    For example, how can someone who is heat sensitive mitigate the impact of fever caused by the vaccine?
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    Other Researchers

    Are symptoms from the vaccination stronger among MS sufferers?

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    Other Researchers

    Is anyone planning on monitoring covid patients to see if Covid causes a rise in MS diagnoses?

    Since covid moves into the CNS, what will be the short-term and long-term consequences for patients both with and without MS. Could this be a new environmental trigger for MS?
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    iConquerMS

    What are the long term side effects of COVID-19 for people with MS?

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    iConquerMS

    Has the COVID era resulted in any positive changes for the MS community?

    For example, has increased availability of telehealth been helpful?
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    iConquerMS

    Does infection with COVID-19 have the potential to cause the onset of MS or trigger an MS relapse?

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    iConquerMS

    Has the COVID19 pandemic affected future work feasibility for those with MS?

    I have not seen any studies of returning to work after the Pandemic for those with MS. For me specifically, it is impossible for me, in all respects. I had been at my job for 24 years and they had made huge accommodations for me as I progressed with my MS over this time. My place of work closed (for good) due to the pandemic and I am currently unable to do what I am trained to do if I were to apply for the same type of work. Any current workplace would not be able to reasonably offer the same accommodations. The pandemic essentially ended my working ability.
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    iConquerMS

    Has COVID-19 changed preference of DMT drug choice for people with MS?

    From the change or delays in timing of infusion or temporary change of DMT usage to accommodate vaccination, is there any effect on choice or preference of DMT for MS patients?
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    iConquerMS

    Have people with MS experienced new cognitive changes after recovering from COVID-19?

    There is emerging evidence that some people who have recovered from COVID-19 have experienced cognitive changes which are similar to the cognitive changes that people with MS experience. It would be interesting to understand the prevalence of these post-COVID cognitive changes among people living with MS.
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    iConquerMS

    How has the COVID-19 Pandemic affected MS management and care?

    Specifically, I'm interested in knowing (1) how many people missed in-person neurology exams/MRIs that may have picked up on subtle/subclinical disease progression? (2) how many patients stopped, interrupted, or altered the dosing schedule of their DMT? (3) have patients become deconditioned due to less access to exercise/PT programs? If so, what are the physical and mental effects?
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    iConquerMS

    How well do the different COVID-19 vaccines work in people with MS?

    Also, does the safety and effectiveness of these vaccines differ based on age, race, ethnicity or MS drug?
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    iConquerMS

    Has COVID-19 isolation affected people with MS?

    If so, do the effects vary based on age, gender, race, ethnicity or MS subtype?
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    iConquerMS

    Do opinions and preferences about COVID-19 vaccination vary by race or ethnicity in people with MS?

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    Other Researchers

    Compared to the general population, are people with MS at greater risk for becoming infected with COVID-19?

    Also, does the risk of COVID-19 infection vary by race or ethnicity in people with MS?
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    iConquerMS

    Are there any mental health changes associated with COVID-19 infection in people with MS?

    If so, do any mental health changes vary by race or ethnicity in people with MS?
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    iConquerMS

    Do any MS drugs appear to affect the course or severity of COVID-19?

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