iConquerMS™ is different in several ways from other MS data-collection efforts, such as PatientsLikeMe and NARCOMS. First, it is a nonprofit endeavor governed by people affected by MS and includes their voice every step of the way. Second, it is centered on research driven by people affected by MS on topics of interest to them. iConquerMS is connected to other people-powered research networks and clinical networks through its strong relationship with the Patient Centered Outcomes Research Institute (PCORI). This gives us the power to easily contribute our data to many research efforts and gives MS researchers access to data from millions of people across the country. While other efforts share some of these qualities, iConquerMS™ is the only MS research initiative that is nonprofit, people-centered and governed, and part of a nationwide research network.